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Rabbit Anti-GSC/Biotin Conjugated antibody (bs-12352R-Bio)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12352R-Bio
英文名称 Rabbit Anti-GSC/Biotin Conjugated antibody
中文名称 生物素标记的同源盒蛋白GSC抗体
别    名 Goosecoid; goosecoid homeobox; GSC; GSC2; GSC_HUMAN; homeobox protein goosecoid-like; homeobox protein goosecoid-2; Homeobox protein goosecoid; GSC 2; GSCL; Homeobox protein goosecoid 2; Homeobox protein goosecoid like.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  信号转导  干细胞  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Rabbit, Sheep, )
产品应用 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human GSC
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Goosecoid is a homeodomain transcription factor with DNA binding specificity identical to that of the anterior morphogen 'bicoid' in Drosophila.During mouse embryogenesis, GSC influences development of the lower mandible and its associated musculature, including the tongue, the nasal cavity, and the nasal pits, as well as components of the inner ear and the external auditory meatus. The GSC gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins.

Function:
Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the paired homeobox family. Bicoid subfamily.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 2928 Human

Entrez Gene: 195333 Mouse

SwissProt: O15499 Human

SwissProt: P56916 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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