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Rabbit Anti-DDX6/AF350 Conjugated antibody (bs-14239R-AF350)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-14239R-AF350
英文名称 Anti-DDX6/AF350
中文名称 AF350标记的ATP依赖RNA解旋酶DDX6抗体
别    名 ATP dependent RNA helicase DDX6; ATP dependent RNA helicase p54; DDX6; DEAD (Asp Glu Ala Asp) box polypeptide 6; DEAD box 6; DEAD box protein 6; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase 54kD); FLJ36338; HLR2; Oncogene RCK; P54; Probable ATP-dependent RNA helicase DDX6; RCK.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞凋亡  转录调节因子  细胞分化  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDX6
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012]

Function:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis and cellular growth and division. In the process of mRNA degradation, DDX6 may play a role in mRNA decapping. It forms a complex with DCP1A, DCP2, EDC3 and EDC4/HEDLS.

Subcellular Location:
Cytoplasm; P-body. Note: Processing bodies (PB).

Database links:

Entrez Gene: 1656 Human

Entrez Gene: 13209 Mouse

Entrez Gene: 500988 Rat

Omim: 600326 Human

SwissProt: P26196 Human

SwissProt: P54823 Mouse

Unigene: 408461 Human

Unigene: 267061 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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