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Rabbit Anti-FLRT3/PE-Cy5.5 Conjugated antibody (bs-12363R-PE-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12363R-PE-Cy5.5
英文名称1 Rabbit Anti-FLRT3/PE-Cy5.5 Conjugated antibody
中文名称 PE-Cy5.5标记的富含亮氨酸跨膜纤连蛋白3抗体
别    名 fibronectin leucine rich transmembrane protein 3; Fibronectin-like domain-containing leucine-rich transmembrane protein 3; FLRT 3; FLRT3; FLRT3_HUMAN; KIAA1469; Leucine-rich repeat transmembrane protein FLRT3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 发育生物学  信号转导  干细胞  细胞分化  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FLRT3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
FLRT3 is a 649 amino acid single-pass type I membrane protein that contains one fibronectin type-III domain and ten leucine-rich repeats and belongs to the fibronectin leucine rich transmembrane protein (FLRT) family. Expressed in heart, liver, lung, kidney, pancreas, brain, placenta and skeletal muscle, FLRT3 is thought to be involved in receptor signaling events and may play a role in both cell adhesion neurite outgrowth. Defects in the gene encoding mouse FLRT3 may lead to ventral closure, headfold fusion and endoderm migration defects, suggesting that FLRT3 is important for proper cell differentiation and development. FLRT3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 20.

Function:
May have a function in cell adhesion and/or receptor signaling.

Subcellular Location:
Membrane; Single-pass type I membrane protein (Probable).

Tissue Specificity:
Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.

Similarity:
Contains 1 fibronectin type-III domain.
Contains 10 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

Database links:
UniProtKB/Swiss-Prot: Q9NZU0.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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