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Rabbit Anti-TBX6/Cy5.5 Conjugated antibody (bs-12281R-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12281R-Cy5.5
英文名称 Rabbit Anti-TBX6/Cy5.5 Conjugated antibody
中文名称 Cy5.5标记的转录因子TBX6抗体
别    名 DFNB 67; DFNB67; T box 6; T box protein 6; T box transcription factor TBX 6; T box transcription factor TBX6; T-box protein 6; T-box transcription factor TBX6; Tbox 6; TBX 6; tbx6; TBX6_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 发育生物学  干细胞  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human TBX6 (241-330aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Members of the T-box (Tbx) gene family share a conserved domain that codes for the T-box, a sequence involved in DNA-binding and protein dimerization. The Tbx gene family is largely conserved throughout metazoan evolution, and is implicated in a variety of developmental processes ranging from the formation of germ layers to the organizational patterning of the central nervous system. In the mouse, Tbx6 is involved in both the specification and patterning of the somites along the entire length of the embryo. Specifically, Tbx6 is expressed in the primitive streak, tail bud, and presomitic mesoderm and is essential for the specification of posterior paraxial mesoderm. In the absence of Tbx6, posterior somites are replaced by ectopic neural tubes.

Function:
Probable transcriptional regulator involved in developmental processes. Could be required for specification of paraxial mesoderm structures during gastrulation.

Subunit:
Forms a dimeric complex with DNA (in vitro).

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus.

Similarity:
Contains 1 T-box DNA-binding domain.

Database links:
UniProtKB/Swiss-Prot: O95947.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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