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Rabbit Anti-TRH/AP Conjugated antibody (bs-10593R-AP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10593R-AP
英文名称 Anti-TRH/AP
中文名称 碱性磷酸酶(AP)标记的促甲状腺素释放激素抗体
别    名 Pro-thyrotropin-releasing hormone; Pro-TRH; Prothyroliberin; Thyrotropin-releasing hormone; TRH; Protirelin; TSH-releasing factor; Thyroliberin; Thyrotropin-releasing factor; TRF; TRH_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  神经生物学  信号转导  生长因子和激素  内分泌病  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, )
产品应用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated human TRH (pGlu-His-Pro-Amide)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013].
(L-Pyroglutamyl-L-histidyl-L-prolinamide)pGlu-His-Pro Amide, C18H26N6O6


Function:
Thyrotropin releasing hormone (TRH) is a tripeptide hormone that stimulates the release of thyroid stimulating hormone and prolactin by the anterior pituitary. TRH is produced by the hypothalamus and travels across the median eminence to the pituitary via the hypophyseal portal system. In addition to the brain, TRH can also be detected in other areas of the body including the gastrointestinal system and pancreatic islets.

Subcellular Location:
Secreted.

Tissue Specificity:
Hypothalamus. Expressed in the hair follicle epithelium (at protein level).

Similarity:
Belongs to the TRH family.

Database links:

Entrez Gene: 7200 Human

Entrez Gene: 22044 Mouse

Entrez Gene: 25569 Rat

Omim: 275120 Human

SwissProt: P20396 Human

SwissProt: Q62361 Mouse

SwissProt: P01150 Rat

Unigene: 1363 Mouse

Unigene: 22 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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