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Rabbit Anti-CPAMD8/Gold Conjugated antibody (bs-14018R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-14018R-Gold
英文名称 Rabbit Anti-CPAMD8/Gold Conjugated antibody
中文名称 胶体金标记的CPAMD8蛋白抗体
别    名 C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8; CPAMD8; CPMD8_HUMAN; K CAP; VIP.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Dog, Cow, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 204kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CPAMD8
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
CPAMD8 belongs to the complement component-3 (C3; MIM 120700)/alpha-2-macroglobulin (A2M; MIM 103950) family of proteins, which are involved in innate immunity and damage control. Complement components recognize and eliminate pathogens by direct binding or by mediating opsonization/phagocytosis and intracellular killing, and A2M is a broad-spectrum protease inhibitor (Li et al., 2004 [PubMed 15177561]).[supplied by OMIM, Mar 2008]

Function:
Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine.

Subcellular Location:
Secreted. Cell membrane.

Post-translational modifications:
Proteolytically cleaved into 2 chains of about 70 and 130 kDa. The fragments are not connected by disulfide bonds.

Similarity:
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
Contains 1 Kazal-like domain.

Database links:

Entrez Gene: 27151 Human

Omim: 608841 Human

SwissProt: Q8IZJ3 Human

Unigene: 631644 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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