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Rabbit Anti-GABRA6/BF350 Conjugated antibody (bs-12063R-BF350)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12063R-BF350
英文名称 Rabbit Anti-GABRA6/BF350 Conjugated antibody
中文名称 BF350标记的G氨基丁酸A型受体α6/GABAA Rα6抗体
别    名 GABA A; GABA A Receptor alpha 6 polypeptide; GABA A receptor alpha 6; GABA A receptor subunit alpha 6; GABA subunit A receptor alpha 6; GABA(A) receptor subunit alpha-6; GABRA 6; GABRA6; Gamma aminobutyric acid A receptor alpha 6; Gamma aminobutyric acid GABA A receptor alpha 6; Gamma aminobutyric acid receptor subunit alpha 6; Gamma-aminobutyric acid receptor subunit alpha-6; GBRA6_HUMAN; MGC116903; MGC116904.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABRA6/GABA A Receptor alpha 6
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]

Function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Subunit:
Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.

Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily.

Database links:

Entrez Gene: 2559 Human

Entrez Gene: 14399 Mouse

Entrez Gene: 29708 Rat

Omim: 137143 Human

SwissProt: Q16445 Human

SwissProt: P16305 Mouse

SwissProt: P30191 Rat

Unigene: 90791 Human

Unigene: 4915 Mouse

Unigene: 29890 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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