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Rabbit Anti-ERAS/Gold Conjugated antibody (bs-4950R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-4950R-Gold
英文名称1 Rabbit Anti-ERAS/Gold Conjugated antibody
中文名称 胶体金标记的胚胎干细胞RAS蛋白抗体
别    名 E ras; E-Ras; ecat5; Embryonic stem cell expressed Ras; Embryonic stem cell-expressed Ras; Eras; ES cell expressed Ras; GTPase ERas; Ha-Ras2; HRAS2; HRASP; MGC126691; MGC126693; OTTHUMP00000065857; RASE_HUMAN; Small GTPase protein E Ras; v Ha ras Harvey rat sarcoma viral oncogene homolog pseudogene; v Ha ras Harvey rat sarcoma viral oncogene homolog 2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  细胞生物  免疫学  发育生物学  染色质和核信号  信号转导  干细胞  G蛋白偶联受体  细胞表面分子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ERAS/HRAS2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
ERAS belongs to the small GTPase superfamily. Ras family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. The ERas gene is expressed in embryonic stem (ES) cells and promotes their in vitro proliferation and tumorigenicity. ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase.

Function:
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells (By similarity).

Subunit:
Interacts with PIK3CD (By similarity).

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side.

Similarity:
Belongs to the small GTPase superfamily. Ras family.

Database links:

Entrez Gene: 3266 Human

Entrez Gene: 353283 Mouse

Entrez Gene: 679682 Rat

Omim: 300437 Human

SwissProt: Q7Z444 Human

SwissProt: Q7TN89 Mouse

Unigene: 447330 Human

Unigene: 250895 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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