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Rabbit Anti-Selenium Binding Protein 1/FITC Conjugated antibody (bs-4200R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-4200R-FITC
英文名称 Anti-Selenium Binding Protein 1/FITC
中文名称 FITC标记的硒结合蛋白1抗体
别    名 56 kDa selenium binding protein; 56 kDa selenium-binding protein; hSBP; LPSB; SBP; SBP1; SBP1_HUMAN; SBP56; Selenbp1; Selenbp2; Selenium binding protein 2; Selenium binding protein1; Selenium-binding protein 1; SELNBP1; SP56.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SBP1/Selenium Binding Protein 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease.

Function:
Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.

Subunit:
Interacts with USP33.

Subcellular Location:
Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=May associate with Golgi membrane. May associate with the membrane of autophagosomes.

Tissue Specificity:
Present in liver and colon (at protein level).

Post-translational modifications:
The N-terminus is blocked.

Similarity:
Belongs to the selenium-binding protein family.

Database links:

Entrez Gene: 8991 Human

Entrez Gene: 20341 Mouse

Entrez Gene: 140927 Rat

Omim: 604188 Human

SwissProt: Q13228 Human

SwissProt: P17563 Mouse

SwissProt: Q8VIF7 Rat

Unigene: 632460 Human

Unigene: 16617 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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