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Rabbit Anti-LONP1/Cy5.5 Conjugated antibody (bs-4245R-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-4245R-Cy5.5
英文名称 Rabbit Anti-LONP1/Cy5.5 Conjugated antibody
中文名称 Cy5.5标记的线粒体离子肽酶1抗体
别    名 Serine protease 15; hLON ATP dependent protease; Lon protease like protein; LonHS; LONP; PIM1; PRSS15; hLON; LON; lon peptidase 1, mitochondrial; LON protease; Mitochondrial ATP dependent protease Lon; Mitochondrial Ion peptidase 1; Protease serine 15.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  染色质和核信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LONP1 (375-420aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
LONP1 encodes a mitochondrial matrix protein in the Lon family of ATP dependent proteases. It binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription.

Subunit:
Homohexamer or homoheptamer. Organized in a ring with a central cavity. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with PEO1 and mitochondrial DNA polymerase subunit POLG.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Duodenum, heart, lung and liver, but not thymus.

Similarity:
Belongs to the peptidase S16 family.
Contains 1 Lon domain.

Database links:

Entrez Gene: 510796 Cow

Entrez Gene: 9361 Human

Entrez Gene: 74142 Mouse

Entrez Gene: 170916 Rat

Omim: 605490 Human

SwissProt: Q59HJ6 Cow

SwissProt: P36776 Human

SwissProt: Q8CGK3 Mouse

SwissProt: Q924S5 Rat

Unigene: 350265 Human

Unigene: 329136 Mouse

Unigene: 146805 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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