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Rabbit Anti-APOH/Cy3 Conjugated antibody (bs-1570R-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1570R-Cy3
英文名称1 Rabbit Anti-APOH/Cy3 Conjugated antibody
中文名称 Cy3标记的载脂蛋白H抗体
别    名 Apolipoprotein H; Activated protein C binding protein; APC inhibitor; APOH; B2G1; beta 2 glycoprotein I; beta 2 glycoprotein I precursor; BG; OTTMUSP00000003033; APOH_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  免疫学  合成与降解  糖蛋白  脂蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Cow, Horse, Rabbit, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ApoH
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Apolipoprotein H is expressed by placental trophoblast cells at high levels. Although the normal physiological role is not known, the protein appears to act as a co-factor for the binding of autoantibodies to phospholipids to trophoblasts, which is a process involved in the pathogenesis of recurrent miscarriage.

Function:
Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by the liver and secreted in plasma.

Post-translational modifications:
N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele.

Similarity:
Contains 4 Sushi (CCP/SCR) domains.

Database links:

Entrez Gene: 350 Human

Entrez Gene: 287774 Rat

Omim: 138700 Human

SwissProt: P02749 Human

SwissProt: P26644 Rat

Unigene: 445358 Human

Unigene: 1824 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

载脂蛋白H(apolipoprotein D,apoH)又称为β2糖蛋白Ⅰ(β2-glycoprotein,β2-GI),是最初是在人血浆的高密度脂蛋白中被分离出来的。apoH在结构上与其他类型的载脂蛋白存在很大的差异,被归入脂肪促成素家族。
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