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Rabbit Anti-phospho-CPI17 alpha (Thr38) /FITC Conjugated antibody (bs-4073R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-4073R-FITC
英文名称 Rabbit Anti-phospho-CPI17 alpha (Thr38) /FITC Conjugated antibody
中文名称 FITC标记的磷酸化蛋白磷酸激酶PKC/CPI-17抗体
别    名 CPI17 alpha (phospho T38); p-CPI17 alpha (phospho T38); 17kDa PKC potentiated inhibitory protein of PP1; CPI 17 alpha; CPI 17; CPI 17alpha; CPI17; CPI-17; PKC potentiated inhibitory protein of PP1; PPP1INL; PPP1R14A; Protein phosphatase 1; Protein phosphatase 1 regulatory (inhibitor) subunit 14A; Protein phosphatase 1 regulatory subunit 14A; Regulatory subunit 14A; 17 kDa PKC-potentiated inhibitory protein of PP1; 17-KDa protein; 17kDa PKC potentiated inhibitory protein of PP1; PKC potentiated inhibitory protein of PP1; PKC potentiated inhibitory protein of PP1, 17-KD; PP14A_HUMAN; Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD; Protein kinase C-potentiated inhibitor protein of 17 kDa; Protein phosphatase 1; Protein phosphatase 1 regulatory (inhibitor) subunit 14A; Regulatory subunit 14A.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 肿瘤  免疫学  信号转导  转录调节因子  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human CPI17 alpha around the phosphorylation site of Thr38
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]

Function:
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.

Similarity:
Belongs to the PP1 inhibitor family.

Database links:

Entrez Gene: 94274 Human

Entrez Gene: 68458 Mouse

Entrez Gene: 114004 Rat

Omim: 608153 Human

SwissProt: Q96A00 Human

SwissProt: Q91VC7 Mouse

SwissProt: Q99MC0 Rat

Unigene: 631569 Human

Unigene: 2343 Mouse

Unigene: 73852 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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