产品编号 | bs-0417R-PE-Cy7 |
英文名称1 | Rabbit Anti-TIMP-3/PE-Cy7 Conjugated antibody |
中文名称 | PE-Cy7标记的金属蛋白酶组织抑制因子-3抗体 |
别 名 | HSMRK222; K222; K222TA2; Metalloproteinase inhibitor 3; TIMP3; TIMP 3; MIG 5 protein; MIG5 protein; Protein MIG 5; SFD; Sorsby fundus dystrophy pseudoinflammatory; TIMP metallopeptidase inhibitor 3; TIMP3; Tissue Inhibitor of Metalloproteinase 3; Tissue inhibitor of metalloproteinases3; TIMP3_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 心血管 细胞生物 神经生物学 信号转导 细胞凋亡 合成与降解 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, ) |
产品应用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 21kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TIMP-3 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 |
background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]. Subunit: Interacts with EFEMP1. Subcellular Location: Secreted, extracellular space, extracellular matrix. Similarity: Belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain. Database links: Entrez Gene: 7078 Human Entrez Gene: 21859 Mouse Omim: 188826 Human SwissProt: P35625 Human SwissProt: P39876 Mouse Unigene: 644633 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 合成与降解(Synthesis and Degradation) 近年来,国内外科研人员对TIMP-3的抗肿瘤作用日益被重视,学者认为:TIMP-3具有强烈促凋亡、抑制血管生成、抗肿瘤浸润作用,TIMP-3与TIMP-1、2且相互间有明显协同抗肿瘤作用 |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |