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Rabbit Anti-Resistin/Cy5.5 Conjugated antibody (bs-0795R-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-0795R-Cy5.5
英文名称1 Rabbit Anti-Resistin/Cy5.5 Conjugated antibody
中文名称 Cy5.5标记的抵抗素抗体
别    名 Adipose tissue specific secretory factor; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; Cysteine rich secreted protein A12 alpha like 2; Cysteine rich secreted protein FIZZ3; FIZZ 3; FIZZ3; Found in inflammatory zone 3; HXCP 1; HXCP1; MGC126603; MGC126609; PRO1199; Resistin delta2; RETN 1; RETN; RETN1; RSTN; UNQ407; XCP 1; XCP1  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  免疫学  神经生物学  信号转导  生长因子和激素  激酶和磷酸酶  糖尿病  内分泌病  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Mouse, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Resistin
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. [provided by RefSeq]

Function:
Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed only in fatty tissues.

Similarity:
Belongs to the resistin/FIZZ family.

Database links:

Entrez Gene: 56729 Human

Entrez Gene: 57264 Mouse

Omim: 605565 Human

SwissProt: Q9HD89 Human

SwissProt: Q99P87 Mouse

Unigene: 283091 Human

Unigene: 1181 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

抵抗素Resistin, 是一种肽激素,富含半胱氨酸的分泌蛋白, 由脂肪细胞分泌的多肽类激素,属于RELM家族,也称之为ADSF(脂肪组织特异性的分泌因子),抵抗素可能是肥胖和胰岛素抵抗之间的重要链接。近期研究结果显示,抵抗素 (Resistin)还是一种重要的脂肪组织旁分泌调质, 参与内血管内皮细胞功能稳态的调节, 在二型糖尿病心血管病变发生发展过程中发挥重要病理生理学作用.
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