| 产品编号 | bs-0280R-PE-Cy5 |
| 英文名称 | Rabbit Anti-PLGF/PE-Cy5 Conjugated antibody |
| 中文名称 | PE-Cy5标记的胎盘生长因子抗体 |
| 别 名 | Placenta growth factor; PGF; PGFL; PIGF; Placental growth factor vascular endothelial growth factor related protein; PlGF 2; PLGF; PlGF2; PLGF_MOUSE; Vascular endothelial growth factor related protein. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 生长因子和激素 转录调节因子 细胞表面分子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Mouse, Rat, Pig, ) |
| 产品应用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 16kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse PLGF |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011] Function: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Subunit: Antiparallel homodimer; disulfide-linked. Also found as heterodimer with VEGFA/VEGF. Subcellular Location: Secreted. The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin. Tissue Specificity: While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas. Post-translational modifications: N-glycosylated. Similarity: Belongs to the PDGF/VEGF growth factor family. Database links: Entrez Gene: 5228 Human Entrez Gene: 18654 Mouse Omim: 601121 Human SwissProt: P49763 Human SwissProt: P49764 Mouse Unigene: 252820 Human Unigene: 4809 Mouse Unigene: 6960 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PLGF胎盘生长因子是血管生长因子家族成员之一（又称：胎盘型血管内皮细胞生长因子），是动脉粥样硬化斑块不稳定的主要炎性激活物，因此它可作为ACS患者风险预测的生物学标志物.尿胎盘生长因子水平可预测先兆子痫危险.研究人员发现，在疾病发作前的6到8周，先兆子痫患者尿液中的胎盘生长因子水平急剧下降,这种新的尿检方法使提前1到2个月预测先兆子痫成为可能。亦有研究人员正在从事胎盘生长因子与肺气肿，胃癌，肠癌等方面的研究。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
