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Rabbit Anti-PIBF/RBITC Conjugated antibody (bs-0420R-RBITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-0420R-RBITC
英文名称 Rabbit Anti-PIBF/RBITC Conjugated antibody
中文名称 罗丹明(RBITC)标记的孕激素诱导阻断因子抗体
别    名 progesterone induced blocking factor; KIAA1008; PIBF 1; PIBF; PIBF1; Progesterone immunomodulatory binding factor 1; Progesterone induced blocking factor 1; PIBF1_HUMAN; RP11 505F3.1; CEP90; C13orf24; RP11-505F3.1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 免疫学  细胞周期蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,  (predicted: Human, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 83kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PIBF
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
C13orf24 is also known as Progesterone-induced-blocking factor 1 (PIBF1). PIBF1 is synthesized by lymphocytes of healthy pregnant women in the presence of progesterone and inhibits arachidonic acid release, by acting on the phospholipase A2 enzyme, inducing a Th2 biased immune response. It also controls NK activity, and modifies the cytokine balance exerting an anti-abortive effect.

Function:
Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.

Tissue Specificity:
Expressed at highest levels in testis. Moderate expression is detected in spleen, thymus, prostate, ovary, small intestine, and colon.

Database links:

Entrez Gene: 10464 Human

Entrez Gene: 52023 Mouse

Entrez Gene: 306104 Rat

Omim: 607532 Human

SwissProt: Q8WXW3 Human

Unigene: 441926 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

孕激素诱导阻断因子又称孕酮诱导的封闭因子性蛋白。
妊娠期间淋巴细胞生成孕酮受体且释放一种称之为孕酮诱导的封闭因子性蛋白(PIBF),PIBF有很强的抗NK细胞活性,PIBF阳性淋巴细胞分泌IL-10。
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