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Rabbit Anti-PACAP-38/Biotin Conjugated antibody (bs-0200R-Bio)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-0200R-Bio
英文名称 Rabbit Anti-PACAP-38/Biotin Conjugated antibody
中文名称 生物素标记的腺苷酸环化酶激活肽-38抗体
别    名 HSPC190; Proapoptotic Caspase Adaptor Protein; PACAP; pERp1; Plasma cell-induced ER protein 1; Plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; Proapoptotic caspase adapter protein; pituitary adenylate cyclase activating polypeptide; PRP-48; Pituitary adenylate cyclase-activating polypeptide 27; PACAP-related peptide; PACAP27; PACAP-27; Pituitary adenylate cyclase-activating polypeptide 38; Pituitary adenylate cyclase-activating polypeptide 38; PACAP38; PACA_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Rat,  (predicted: Mouse, Pig, Cow, Sheep, )
产品应用 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 5kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PACAP-38
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Pituitary adenylate cyslase Activating polypeptide-27/38, PACAP-27/38 is a neuropeptide that has substantial sequence homology to vasoactive intestinal peptide (VIP).Both VIPand PACAP-38are equipotent at the VCAP-2 receptor, while PAC AP -38 is equipotent to PACAP-27 and more potent than VIP at the PAC-1receptor. The function of PACAP is Stimulates adenylate cyclase in pituitary cells. It belongs to the glucagon family.

Function:
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells.

Subunit:
Interacts with ADCYAP1R1 (via N-terminal extracellular domain).

Subcellular Location:
Secreted.

Similarity:
Belongs to the glucagon family.

Database links:

Entrez Gene: 116 Human

Entrez Gene: 11516 Mouse

Entrez Gene: 414283 Pig

Entrez Gene: 24166 Rat

Omim: 102980 Human

SwissProt: P18509 Human

SwissProt: O70176 Mouse

SwissProt: P41535 Pig

SwissProt: P13589 Rat

Unigene: 531719 Human

Unigene: 727476 Human

Unigene: 3407 Mouse

Unigene: 37400 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

腺苷酸环化酶激活肽是一种可激活垂体腺苷酸环化酶的多肽,有PACAP-27和 PACAP-38两种形式,他们共同具有N端27个氨基酸,属于PACAP/glucagon超级家族。在中枢神经系统分布广泛,其中以下丘脑含量最高。
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