| 产品编号 | bs-1095R-BF488 |
| 英文名称1 | Rabbit Anti-Orexin receptor 1+2/BF488 Conjugated antibody |
| 中文名称 | BF488标记的丘脑分泌素受体1+2/食欲素受体1+2抗体 |
| 别 名 | Orexin Receptor 1 and 2; Orexin receptor 1 + 2; Orexin Receptor 2; HCRTR 1; HCRTR1; Hypocretin receptor type 1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1r; OX1R_HUMAN; Hcrtr2; Hypocretin (orexin) receptor 2; Hypocretin receptor 2; Hypocretin receptor type 2; Orexin receptor 2; Orexin receptor type 2; Ox-2-R; Ox2-R; Ox2r; OX2R_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 信号转导 通道蛋白 细胞膜受体 内分泌病 G蛋白偶联受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 产品应用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 50kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Orexin receptor 1/2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009] Function: Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 3061 Human Entrez Gene: 230777 Mouse Omim: 602392 Human SwissProt: O43613 Human SwissProt: P58307 Mouse Unigene: 388226 Human Unigene: 246595 Mouse Unigene: 88262 Rat Entrez Gene: 3062 Human Entrez Gene: 387285 Mouse Omim: 602393 Human SwissProt: O43614 Human SwissProt: P58308 Mouse Unigene: 151624 Human Unigene: 699147 Human Unigene: 335300 Mouse Unigene: 9893 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 食欲素受体(OXR)Orexin receptor—是一种G蛋白偶合受体. 下丘脑是调节饮食及能量平衡的中枢.学者认为：在下丘脑可促进食欲且来源于同一前体的两种新神经肽:食欲素A和B,它们可激活两种密切相关且与G蛋白偶联的细胞表面受体(OX1R,OX2R).含Orexin的神经细胞在下丘脑腹外侧呈对称的不连贯分布. 在饮食反馈调节中具有重要作用.食欲素与其它影响进食的神经肽之间存在错综复杂的关系.它在增加摄食、饮水、调节睡眠觉醒周期、生殖、体温、血压和感觉等方面有广泛作用. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
