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Rabbit Anti-NPPC/Atrial natriuretic peptide/BF555 Conjugated antibody (bs-1069R-BF555)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1069R-BF555
英文名称 Rabbit Anti-NPPC/Atrial natriuretic peptide/BF555 Conjugated antibody
中文名称 BF555标记的C型钠利尿多肽抗体
别    名 NPPC; ANP; C type natriuretic peptide precursor; C-type natriuretic peptide; CNP-22; CNP-29; CNP-53; CNP; CNP2; Natriuretic peptide precursor C; pro-natriuretic peptide; ANFC_HUMAN; CNP-53; CNP2; Natriuretic peptide C.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human proCNP (75-126aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; MIM 600295), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.

Function:
Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3

Subcellular Location:
Secreted.

Similarity:
Belongs to the natriuretic peptide family.

Database links:

Entrez Gene: 4880 Human

Entrez Gene: 18159 Mouse

Entrez Gene: 114593 Rat

Omim: 600296 Human

SwissProt: P23582 Human

SwissProt: Q61839 Mouse

SwissProt: P55207 Rat

Unigene: 247916 Human

Unigene: 12802 Mouse

Unigene: 10637 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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