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Rabbit Anti-HN1/PE Conjugated antibody (bs-9069R-PE)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-9069R-PE
英文名称1 Rabbit Anti-HN1/PE Conjugated antibody
中文名称 PE标记的雄激素调节蛋白2抗体
别    名 Androgen regulated protein 2; Androgen-regulated protein 2; ARM2; Hematological and neurological expressed 1; Hematological and neurological expressed 1 protein; HN1; HN1_HUMAN; HN1A.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Rabbit, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HN1/ARM2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Hematological and neurological expressed 1 protein (HN1) is a 154 amino acid member of the HN1 family. HN1 has been proposed to play a role in embryo development, specifically hemopoietic cell and neurological development. Localized to the nucleus, HN1 is expressed in many fetal and adult tissues, with highest levels of expression in brain, colon, prostate, testis, thymus, skeletal muscle, peripheral blood cells and placenta. HN1 has been identified to have processed pseudogenes in the mouse, rat and human genomes, suggesting that HN1 and its pseudogenes represent a novel gene family. Three isoforms of HN1 exist as a result of alternative splicing events. HN1L (hematological and neurological expressed 1-like protein), also known as C16orf34 or L11, is a 190 amino acid protein that belongs to the HN1 family. Localizing to the cytoplasm as well as the nucleus, HN1L is expressed in liver, kidney, prostate, testis and uterus. HN1L gets upregulated in certain carcinomas, including squamous cell carcinoma (SCC), adenocarcinoma (AC), adenosquamous cell carcinoma (ASCC) and bronchioalveolar carcinoma (BAC), and is also expressed in breast and uterine tumors. HN1L, along with HN1, may be involved in embryo development.

Subcellular Location:
Nucleus

Tissue Specificity:
Expressed in testis, skeletal muscle, thymus, prostate, colon, peripheral blood cells, brain and placenta.

Post-translational modifications:
Isoform 3 initiator methionine is either acetylated or removed. In the latter case, the new N-terminal amino acid is then N-acetylated.

Similarity:
Belongs to the HN1 family.

Database links:

Entrez Gene: 51155 Human

Entrez Gene: 15374 Mouse

Entrez Gene: 287828 Rat

SwissProt: Q9UK76 Human

SwissProt: P97825 Mouse

SwissProt: Q6AXU6 Rat

Unigene: 532803 Human

Unigene: 1775 Mouse

Unigene: 198910 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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