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Rabbit Anti-BRN4/HRP Conjugated antibody (bs-8202R-HRP)
订购热线:400-901-9800
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-8202R-HRP
英文名称 Anti-BRN4/HRP
中文名称 辣根过氧化物酶标记的脑转录因子4蛋白抗体
别    名 class 3; transcription factor 4; Brain specific homeobox POU domain protein 4; Brain-4; Brain-specific homeobox/POU domain protein 4; BRAIN4; Brn-4; BRN4; DFN3; Oct-9; Octamer-binding protein 9; Octamer-binding transcription factor 9; OTF-9; OTF9; PO3F4_HUMAN; POU domain; POU domain class 3 transcription factor 4; POU3F4.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  神经生物学  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BRN4/POU3F4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2) . A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness.

Function:
Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.

Subcellular Location:
Nucleus.

Tissue Specificity:
Brain specific.

DISEASE:
Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2) [MIM:304400]. A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness.

Similarity:
Belongs to the POU transcription factor family. Class-3 subfamily.
Contains 1 homeobox DNA-binding domain.
Contains 1 POU-specific domain.

Database links:

Entrez Gene: 5456 Human

Entrez Gene: 18994 Mouse

Entrez Gene: 29589 Rat

Omim: 300039 Human

SwissProt: P49335 Human

SwissProt: P62515 Mouse

SwissProt: P62516 Rat

Unigene: 2229 Human

Unigene: 405149 Mouse

Unigene: 56946 Mouse

Unigene: 33030 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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