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Rabbit Anti-BXDC2/RBITC Conjugated antibody (bs-8436R-RBITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-8436R-RBITC
英文名称 Rabbit Anti-BXDC2/RBITC Conjugated antibody
中文名称 罗丹明(RBITC)标记的BXDC2蛋白抗体
别    名 BRIX; Brix domain containing 2; Brix domain containing protein 2; BRIX1; BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); FLJ11100; Ribosome biogenesis protein Brix; BRX1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BXDC2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
BXDC2 is a 306 amino acid protein encoded by the human gene BXDC2. BXDC2 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region that is homologous to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes BXDC5, BXDC1 and PPAN. This complex is required for the biogenesis of the 60S ribosomal subunit. BXDC2 exhibits the same functions as Pitx1.

Function:
Required for biogenesis of the 60S ribosomal subunit.

Subcellular Location:
Nucleus, nucleolus.

Similarity:
Belongs to the BRX1 family.
Contains 1 Brix domain.

Database links:

Entrez Gene: 55299 Human

Entrez Gene: 67832 Mouse

SwissProt: Q3SZZ0 Cow

SwissProt: Q8TDN6 Human

SwissProt: Q9DCA5 Mouse

Unigene: 718510 Human

Unigene: 28057 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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