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Rabbit Anti-SLCO2A1/PE Conjugated antibody (bs-4710R-PE)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-4710R-PE
英文名称 Rabbit Anti-SLCO2A1/PE Conjugated antibody
中文名称 PE标记的溶质载体蛋白家族21成员2抗体
别    名 MATR1; Matrin F/G 1; OATP2A1; PGT; SO2A1_HUMAN; PHOAR2; Prostaglandin transporter; SLC21A2; Solute carrier family 21 (prostaglandin transporter) member 2; Solute carrier family 21 member 2; Solute carrier organic anion transporter family member 2A1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  信号转导  通道蛋白  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PGT/Slco2a1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The organic anion transporting polypeptide (OATP) family of proteins play a role in drug absorption, distribution and excretion. OATP proteins mediate the uptake of a broad range of substrates, including bile salts, hormones, drugs and antibiotics, and they are expressed in various tissues, such as gut, brain, kidney and liver. PGT, also known as SLCO2A1 (solute carrier organic anion transporter family, member 2A1), SLC21A2 or OATP2A1, is a 643 amino acid multi-pass membrane protein that belongs to the organic anion transporter family. Expressed ubiquitously, PGT is thought to mediate the release, transepithelial transport and clearance of prostaglandins from cells to other areas of the body. The gene encoding PGT maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

Function:
May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the organo anion transporter (TC 2.A.60) family. Contains 1 Kazal-like domain.

Database links:

Entrez Gene: 6578 Human

Omim: 601460 Human

SwissProt: Q92959 Human

Unigene: 518270 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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