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Rabbit Anti-CYBR1/FITC Conjugated antibody (bs-8297R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-8297R-FITC
英文名称 Rabbit Anti-CYBR1/FITC Conjugated antibody
中文名称 FITC标记的细胞色素B还原酶1抗体
别    名 CYBR-1; CYBR 1; CYBR1_HUMAN; CYBRD 1; CYBRD1; Cytochrome b reductase 1; DCYTB; DKFZp564E227; Duodenal cytochrome b; Ferric chelate reductase 3; Ferric-chelate reductase 3; FLJ23462; FRRS3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CYBR1/Cytochrome b reductase 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells.

Function:
Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Present in erythrocyte membranes (at protein level). Also expressed in respiratory epithelium.

Similarity:
Contains 1 cytochrome b561 domain.

Database links:

UniProtKB/Swiss-Prot: Q53TN4.1

Entrez Gene: 79901 Human

Entrez Gene: 73649 Mouse

Entrez Gene: 295669 Rat

Omim: 605745 Human

SwissProt: Q53TN4 Human

SwissProt: Q925G2 Mouse

SwissProt: Q5RKJ2 Rat

Unigene: 726027 Human

Unigene: 741213 Human

Unigene: 45435 Mouse

Unigene: 203500 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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