| 产品编号 | bs-7888R-Bio |
| 英文名称1 | Rabbit Anti-Cyclin L/Biotin Conjugated antibody |
| 中文名称 | 生物素标记的周期素L抗体 |
| 别 名 | Ania 6a; BM 001; CCNL 1; CCNL1; CCNL1_HUMAN; Cyclin L ania 6a; Cyclin L; Cyclin L gamma; Cyclin L1; Cyclin-L; Cyclin-L1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 细胞周期蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, Chimpanzee, mpanzee) |
| 产品应用 | WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 60kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cyclin L/CCNL1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21. Tissue specificity;Ubiquitous with higher level in thymus. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC). Function: Transcriptional regulator which participates inregulating the pre-mRNA splicing process. Seems to be involved inthe regulation of RNA polymerase II (pol II). Functions inassociation with cyclin-dependent kinases (CDKs) and has a role inthe second step of splicing. May be a candidate proto-oncogene inhead and neck squamous cell carcinomas (HNSCC). Inhibited by theCDK-specific inhibitor p21. Subunit: Interacts with POLR2A via its hyperphosphorylatedC-terminal domain (CTD) (By similarity). Interacts with CDK11A,CDK11B, CDK12, CDK13 and SFRS2. Subcellular Location: Nucleus speckle (By similarity). Note=Morespecifically found in nuclear intrachromatin granules clusters(IGC), also called nuclear speckles, which are storage compartmentsfor nuclear proteins involved in mRNA processing (By similarity). Tissue Specificity: Ubiquitous with higher level in thymus.Overexpression in primary tumors of head and neck squamous cellcarcinomas (HNSCC). Similarity: Belongs to the cyclin family. Cyclin L subfamily. Database links: UniProtKB/Swiss-Prot: Q9UK58.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
