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Rabbit Anti-BMPER/APC Conjugated antibody (bs-6910R-APC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6910R-APC
英文名称1 Rabbit Anti-BMPER/APC Conjugated antibody
中文名称 APC标记的BMP内皮细胞调节蛋白抗体
别    名 BMP binding endothelial regulator; BMP binding endothelial regulator precursor protein; Bone morphogenetic protein binding endothelial cell precursor derived regulator; CRIM3; Crossveinless 2; CV 2; CV2; hCV2; Protein crossveinless 2; BMPER_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  免疫学  信号转导  干细胞  生长因子和激素  细胞周期蛋白  转录调节因子  内皮细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Rabbit, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 72kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BMPER
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011].
BMPER is a BMP-binding protein that is expressed by endothelial cell precursors, has BMP-antagonizing activity, and may play a role in endothelial cell differentiation by modulating local BMP activity. It may also regulate BMP responsiveness in osteoblasts and chondrocytes.

Subunit:
Interacts with BMP4.

Subcellular Location:
Secreted.

Tissue Specificity:
Highly expressed in lung, and brain and also in primary chondrocytes.

Similarity:
Contains 1 TIL (trypsin inhibitory-like) domain. Contains 5 VWFC domains. Contains 1 VWFD domain.

Database links:

Entrez Gene: 168667 Human

Entrez Gene: 73230 Mouse

Entrez Gene: 300455 Rat

Omim: 608699 Human

SwissProt: Q8N8U9 Human

SwissProt: Q8CJ69 Mouse

Unigene: 660998 Human

Unigene: 735847 Human

Unigene: 335020 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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