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Rabbit Anti-RCL/Gold Conjugated antibody (bs-7827R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-7827R-Gold
英文名称 Rabbit Anti-RCL/Gold Conjugated antibody
中文名称 胶体金标记的c-Myc应答蛋白抗体
别    名 c Myc responsive; c Myc responsive protein Rcl; C6orf108; Chromosome 6 open reading frame 108; Putative c Myc responsive; RCL_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  细胞周期蛋白  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 19kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RCL/c Myc responsive
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
This gene was identified on the basis of its stimulationby c-Myc protein. The latter is a transcription factor thatparticipates in the regulation of cell proliferation,differentiation, and apoptosis. The exact function of this gene isnot known but studies in rat suggest a role in cellularproliferation and c-Myc-mediated transformation. Two alternativetranscripts encoding different proteins have been described.[provided by RefSeq, Jul 2008].

Function:
Catalyzes the cleavage of the N-glycosidic bond ofdeoxyribonucleoside 5'-monophosphates to yield deoxyribose5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside5'-monophosphates containing purine bases are preferred to thosecontaining pyrimidine bases (By similarity).

Subunit:
Monomer and homodimer (By similarity).

Subcellular Location:
Nucleus (By similarity). Cytoplasm.

Tissue Specificity:
Expressed at low levels in brain, colon, lung,peripheral blood leukocytes, placenta, small intestine, and thymus.Expressed at high levels in heart, kidney, liver, skeletal muscleand spleen. Overexpressed in a significant proportion of breastcancers.

Similarity:
Belongs to the deoxyribonucleoside 5'-monophosphateN-glycosidase family

Database links:
UniProtKB/Swiss-Prot: O43598.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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