产品编号 | bs-7780R-Gold |
英文名称 | Rabbit Anti-CAPH/Gold Conjugated antibody |
中文名称 | 胶体金标记的染色体相关蛋白H抗体 |
别 名 | Barren Drosophila Homolog of 1; Barren homolog protein 1; BRRN; CAP H; CAPH; Chromosome associated protein H; Condensin complex subunit 2; Condensin subunit 2; Condesin; HCAP H; mCAP H; NCAPH; Non SMC condensin I complex subunit H; XCAP H homolog; CND2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul(10nm 15nm 35nm) |
研究领域 | 细胞生物 信号转导 细胞周期蛋白 转录调节因子 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, ) |
产品应用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 82kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human BRRN1/CAPH |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存条件 | Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles. |
产品介绍 |
background: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Subunit: Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG. Subcellular Location: CNucleus. Cytoplasm. Chromosome. Tissue Specificity: Widely expressed at low level. Expressed in proliferating cells. Post-translational modifications: Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPD2 and NCAPG subunits, activates the condensin complex and is required for chromosome condensation (By similarity). Similarity: Belongs to the CND2 (condensin subunit 2) family. Database links: UniProtKB/Swiss-Prot: Q15003.3 Entrez Gene: 23397 Human Entrez Gene: 215387 Mouse Omim: 602332 Human SwissProt: Q15003 Human SwissProt: Q8C156 Mouse Unigene: 308045 Human Unigene: 29786 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |