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Rabbit Anti-SEPT10/Cy7 Conjugated antibody (bs-7770R-Cy7)
~~~促销,代码KT202502A~~~
~~~促销,代码KT202502B~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-7770R-Cy7
英文名称 Rabbit Anti-SEPT10/Cy7 Conjugated antibody
中文名称 Cy7标记的细胞分化蛋白SEPT10抗体
别    名 SEPT 10; SEPT-10; Septin 10; Septin-10; Septin 10; SEP10_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  细胞周期蛋白  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Chicken, Pig, Horse, Rabbit, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEPT10
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The SEPT10 gene encodes a member of the septin family of cytoskeletal proteins which have GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. Alternate splicing results in two transcript variants encoding different isoforms.

Function:
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).

Subunit:
Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity).

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Note=Using a GFP-fusion protein, detected in the nucleus (PubMed:12711328).

Tissue Specificity:
Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.

Similarity:
Belongs to the septin family.

Database links:

Entrez Gene: 151011 Human

Entrez Gene: 103080 Mouse

Omim: 611737 Human

SwissProt: Q9P0V9 Human

SwissProt: Q8C650 Mouse

Unigene: 469615 Human

Unigene: 346842 Mouse

Unigene: 397041 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

SEPTIN(SEPT)家族是细胞骨架蛋白的一种,具有GTPase的活性。经研究发現,SEPT参与细胞核分裂、细胞膜的运输以及构成细胞骨架。
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