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Rabbit Anti-AUP1/Gold Conjugated antibody (bs-7550R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-7550R-Gold
英文名称 Rabbit Anti-AUP1/Gold Conjugated antibody
中文名称 胶体金标记的原始广泛存在蛋白1抗体
别    名 AA589454; AUP 1; AUP1; AUP1_HUMAN; Ancient ubiquitous protein 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 心血管  细胞生物  细胞周期蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AUP1/Ancient ubiquitous protein 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Ancient ubiquitous protein 1 (AUP1) contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. It has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits.

Function:
May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.

Subunit:
Identified in a complex that contains SEL1L, OS9, FAF2/UBXD8, UBE2J1/UBC6E and AUP1. Interacts with the cytoplasmic tail of ITGA2B, ITGA1, ITGA2, ITGA5, ITGAV and ITGAM.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type III membrane protein; Cytoplasmic side.

Tissue Specificity:
Detected in blood platelets and leukocytes (at protein level). Ubiquitous. Highly expressed in placenta, liver, kidney, skeletal muscle, heart and brain.

Similarity:
Belongs to the AUP1 family.
Contains 1 CUE domain.

Database links:

Entrez Gene: 550 Human

Entrez Gene: 11993 Mouse

Entrez Gene: 680423 Rat

Omim: 602434 Human

SwissProt: Q9Y679 Human

SwissProt: P70295 Mouse

SwissProt: A1L134 Rat

Unigene: 411480 Human

Unigene: 386752 Mouse

Unigene: 198163 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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