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Rabbit Anti-Myosin light chain (phospho S20)/PE-Cy7 Conjugated antibody (bs-7052R-PE-Cy7)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-7052R-PE-Cy7
英文名称1 Rabbit Anti-Myosin light chain (phospho S20)/PE-Cy7 Conjugated antibody
中文名称 PE-Cy7标记的磷酸化肌球蛋白调节多肽9(平滑肌亚型)抗体
别    名 MYL9 (phospho S20); p-MLC(Ser20); phospho-MLC(Ser20); p-Myosin light chain(Ser20); MYL9_HUMAN; Myosin regulatory light polypeptide 9; 20 kDa myosin light chain; LC20; MLC-2C; Myosin RLC; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; MLC2; MRLC1; MYRL2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 心血管  信号转导  干细胞  细胞骨架  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human MYL9 around the phosphorylation site of Ser20
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Myosin light chain (MLC) is a subunit of the conventional myosins (e.g. myosin II). In smooth muscle and non-muscle cells conventional myosins mediate a wide variety of contractile events including cytokinesis, cell motility, and smooth muscle contraction. MLC is phosphorylated by multiple serine-threonine kinases such as Rho-kinase and PAK, however myosin light chain kinase (MLCK) acts as the primary kinase. Contractile activity of conventional myosins is regulated by phosphorylation of MLC on several residues.

Subunit:
Myosin is an hexamer of 2 heavy chains and 4 light chains.

Tissue Specificity:
Smooth muscle tissues and in some, but not all, nonmuscle cells.

Similarity:
Contains 3 EF-hand domains.

Database links:

Entrez Gene: 10398 Human

Entrez Gene: 98932 Mouse

Entrez Gene: 296313 Rat

Omim: 609905 Human

SwissProt: P20689 Human

SwissProt: P24844 Human

SwissProt: Q9CQ19 Mouse

SwissProt: Q64122 Rat

Unigene: 504687 Human

Unigene: 271770 Mouse

Unigene: 228729 Rat

Unigene: 6870 Rat




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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