产品编号 | bs-1062R-RBITC |
英文名称 | Rabbit Anti-ADRA2/RBITC Conjugated antibody |
中文名称 | 罗丹明(RBITC)标记的ADRA2肾上腺素能受体2抗体 |
别 名 | alpha-2A adrenergic receptor; alpha 2a Adrenergic Receptor; ADRA2A; ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32; RATRG20; RG20; Adrenergic alpha 2A receptor; Alpha 2AAR subtype C10; OTTHUMP00000058849; ADA2A_HUMAN; Alpha-2A adrenergic receptor; Alpha-2 adrenergic receptor subtype C10; Alpha-2A adrenoreceptor; Alpha-2A adrenoceptor; Alpha-2AAR. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 神经生物学 生长因子和激素 细胞膜受体 G蛋白偶联受体 G蛋白信号 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, ) |
产品应用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 50kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ADRA2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 |
background: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha 2A, alpha 2B, and alpha 2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha 2A and alpha 2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha 2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha 2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha 2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq]. Function: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. Subcellular Location: Cell membrane. Similarity: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2A sub-subfamily. Database links: Entrez Gene: 150 Human Entrez Gene: 11551 Mouse Entrez Gene: 266750 Zebrafish Omim: 104210 Human SwissProt: P08913 Human SwissProt: Q01338 Mouse SwissProt: Q1L8Y8 Zebrafish SwissProt: Q90WY4 Zebrafish Unigene: 249159 Human Unigene: 235195 Mouse Unigene: 170171 Rat Unigene: 30878 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |