| 产品编号 | bs-0752R-BF647 |
| 英文名称 | Rabbit Anti-HLA G/BF647 Conjugated antibody |
| 中文名称 | BF647标记的人类白细胞抗原G抗体 |
| 别 名 | B2 microglobulin; DADB-15K14.8; HLA 6.0; HLA 60; HLA class I histocompatibility antigen alpha chain G; HLA class I histocompatibility antigen alpha chain G precursor; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G; HLA G antigen; HLA G histocompatibility antigen class I G; HLA G protein; HLA G2.2; HLA G3; HLA-G; HLA-G histocompatibility antigen, class I; HLA60; HLAG; HLAG_HUMAN; Human Leukocyte Antigen G Histocompatability Antigen Class 1; Lymphocyte antigen; Major histocompatibility complex class I G; MHC class I antigen; MHC class I antigen G; MHC class Ib antigen; MHC G; Murine homolog of Qa; T Cell A Locus; T-cell A locus; TCA. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 免疫学 细胞表面分子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Rat, |
| 产品应用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from the middle of human HLA-G |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008] Subunit: Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Homodimer; disulfide-linked. Binds to LILRB1 and LILRB2. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in trophoblasts. Similarity: Belongs to the MHC class I family. Contains 1 Ig-like C1-type (immunoglobulin-like) Database links: Entrez Gene: 3135 Human Omim: 142871 Human SwissProt: P17693 Human Unigene: 512152 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 人类白细胞抗原G/组织相容性白细胞抗原G(Human Leukocyte Antigen-G, HLA-G )是一种非典型的白细胞抗原Ⅰ族组织相溶性抗原。该抗原在正常情况下仅在胎盘的绒毛膜表达。在病理情况下HLA-G只在某些癌细胞表达，在正常组织或良性肿瘤则很少表达.因此, HLA-G是一个具有高度肿瘤特异性的肿瘤标志物。 近年研究认为HLA—G作为免疫耐受分子，在肿瘤免疫逃逸中可能具有重要作用. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
