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Rabbit Anti-Centromeric histone H3-like protein-2/PE-Cy5.5 Conjugated antibody (bs-0483R-PE-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-0483R-PE-Cy5.5
英文名称1 Rabbit Anti-Centromeric histone H3-like protein-2/PE-Cy5.5 Conjugated antibody
中文名称 PE-Cy5.5标记的组蛋白H3样抗体
别    名 centromere-specific H3 variant protein; Centromeric histone H3-like protein 2; Centromeric histone H3-like protein-2; cenp-A; A4PIF1_BRAJU.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 植物抗体 
研究领域 肿瘤  免疫学  发育生物学  转录调节因子  植物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Brassica juncea Centromeric histone H3-like protein-2 N-terminus
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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