产品编号 | bs-0540R-Gold |
英文名称 | Rabbit Anti-HAI-1/Gold Conjugated antibody |
中文名称 | 胶体金标记的肝细胞生长因子激活物抑制剂/HGFA Inhibitor 1抗体 |
别 名 | Hepatocyte Growth Factor Activator Inhibitor 1; Spint1; Hai1; HGFA Inhibitor 1; HAI-1; SPIT1_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul(10nm 15nm 35nm) |
研究领域 | 肿瘤 免疫学 激酶和磷酸酶 细胞膜受体 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human, Mouse, Rat, ) |
产品应用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 55kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HAI-1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存条件 | Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles. |
产品介绍 |
background: HGFA Inhibitor 1 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HGFA Inhibitor 1 also inhibits trypsin, and MTSP-1 (Matriptase), a serine proteinase that also activates HGF. HGFB Inhibitor 1 is a splice variant of HGFA Inhibitor 1, and contains a 16 amino acid insert after the first kringle domain, relative to the HGFA Inhibitor 1 sequence. Function: Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14). Subunit: Interacts with HGFAC. Subcellular Location: Secreted. Similarity: Contains 2 BPTI/Kunitz inhibitor domains. Contains 1 LDL-receptor class A domain. Contains 1 MANSC domain. Database links: Entrez Gene: 6692 Human Omim: 605123 Human SwissProt: O43278 Human Unigene: 233950 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. HAI-1 是一种含两个 Kunitz 域的跨膜蛋白,可抑制由细胞膜分泌的并且以游离形式存在的 HGFA 。 HAI-1 也可以作用于其它丝氨酸蛋白酶. HAI-1 主要在胎盘、肾、胰腺、前列腺和小肠,也有报道称 HAI-1 会在肝癌中表达。 |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |