| 产品编号 | bs-1235R-BF594 |
| 英文名称 | Rabbit Anti-Hyaluronidase-1/BF594 Conjugated antibody |
| 中文名称 | BF594标记的透明质酸酶/玻璃酸酶抗体 |
| 别 名 | HYA1; HYAL PH-20; HYAL PH20; HYAL1; HYAL3; HYAL5; Haase; Hyaluronidase PH-20; MGC26532; PH-20 Hyaluronidase; PH20; Hyaluronidase PH20; PH20 Hyaluronidase; SPAG15; SPAM-1; SPAM1;Sperm adhesion molecule 1; Sperm surface protein PH-20; Sperm surface protein PH20; zona pellucida binding. LUCA-3; HYAL1_HUMAN; HYAL 1; Hyal-1; HYAL1; HYAL1_HUMAN; Hyaluronidase 1; Hyaluronidase-1; Hyaluronoglucosaminidase 1; Hyaluronoglucosaminidase-1; Hyaluronoglucosaminidase1; LUCA 1; LUCA-1; LUCA1; Lung carcinoma protein 1; MGC45987; NAT6; Plasma hyaluronidase; Tumor suppressor LUCA 1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, (predicted: Mouse, Rat, ) |
| 产品应用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 45kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from rat Haase |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: Hyaluronidase degrades hyaluronic acid, which is an important structural proteoglycan found in basement membranes and also extracellular matrices. There are six members of the hyaluronidase family. Hyaluronidase PH20 is a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane and plays a role in sperm penetration through the the hyaluronic acid-rich cumulus cell layer surrounding the oocyte. Abnormal expression of this gene has been implicated in degradation of basement membranes leading to tumor invasion and metastasis. Function: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth. Subcellular Location: Secreted. Lysosome. Tissue Specificity: Highly expressed in liver, kidney, lung and skin. Similarity: Belongs to the glycosyl hydrolase 56 family. Contains 1 EGF-like domain. Database links: Entrez Gene: 3373 Human Entrez Gene: 15586 Mouse Omim: 607071 Human SwissProt: Q12794 Human SwissProt: Q91ZJ9 Mouse Unigene: 75619 Human Unigene: 10305 Mouse Unigene: 475658 Mouse Unigene: 124438 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. HAase是一种具有高度底物特异性的蛋白酶，使透明质酸产生低分子化作用的酶之总称,可以特异地作用于透明质酸，通过裂解葡萄糖胺和葡萄糖醛酸的分子键而将透明质酸分解为二糖成分，引起透明质酸的解聚和降解，透明质酸分子从胶原细纤维间隙中释放出来并重新分布，主要定位于细胞外基质影响细胞的增殖、分化及迁移,并在胚胎发育和肿瘤发生发展过程中发挥作用,因而它在胚胎发育、血管形成、免疫监视以及肿瘤发生发展过程中起着重要作用。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
