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Rabbit Anti-GPA33/Gold Conjugated antibody (bs-1226R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-1226R-Gold
英文名称 Rabbit Anti-GPA33/Gold Conjugated antibody
中文名称 胶体金标记的糖蛋白33抗体
别    名 Cell surface A33 antigen precursor; A33; Cell surface A33 antigen; Gpa33; GPA33_HUMAN; Transmembrane glycoprotein A33; Glycoprotein A33 (transmembrane); MGC129986; MGC129987; glycoprotein A33 transmembrane.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPA33 C-terminus
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008]

Function:
May play a role in cell-cell recognition and signaling.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed in normal gastrointestinal epithelium and in 95% of colon cancers.

Post-translational modifications:
N-glycosylated, contains approximately 8 kDa of N-linked carbohydrate.
Palmitoylated.

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 10223 Human

Omim: 602171 Human

SwissProt: Q99795 Human

Unigene: 651244 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

GPA33是胃肠道上皮细胞特异性表达的跨膜糖蛋白,在95%以上的大肠癌、63%的胃癌和50%的胰腺癌中表达。
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