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Rabbit Anti-OXCT1/Gold Conjugated antibody (bs-5089R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-5089R-Gold
英文名称 Rabbit Anti-OXCT1/Gold Conjugated antibody
中文名称 胶体金标记的含氧酸辅酶A转移酶1抗体
别    名 mitochondrial; 3 oxoacid CoA transferase 1; 3-oxoacid-CoA transferase 1; OXCT; Oxct1; SCOT; Scot S; Scot-S; SCOT1_HUMAN; Somatic type succinyl CoA:3 oxoacid CoA transferase; Somatic-type succinyl-CoA:3-oxoacid-CoA-transferase; Succinyl CoA:3 ketoacid CoA transferase; Succinyl CoA:3 ketoacid coenzyme A transferase 1 mitochondrial; Succinyl CoA:3 oxoacid CoA transferase; Succinyl-CoA:3-ketoacid-coenzyme A transferase 1; EC 2.8.3.5 antibody.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  细胞生物  转录调节因子  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human OXCT1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Function:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts.

DISEASE:
Defects in OXCT1 are a cause of SCOT deficiency (SCOTD) [MIM:245050].

Similarity:
Belongs to the 3-oxoacid CoA-transferase family.

Database links:

Entrez Gene: 5019 Human

Entrez Gene: 67041 Mouse

Entrez Gene: 690163 Rat

Omim: 601424 Human

SwissProt: P55809 Human

SwissProt: Q9D0K2 Mouse

SwissProt: B2GV06 Rat

Unigene: 278277 Human

Unigene: 13445 Mouse

Unigene: 98472 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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