| 产品编号 | bs-0168R-Gold |
| 英文名称 | Rabbit Anti-GFRA4/Gold Conjugated antibody |
| 中文名称 | 胶体金标记的GDNF家族受体α4抗体 GDNFRα4 |
| 别 名 | Persephin receptor; GDNF family receptor alpha 4; GDNF family receptor alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR alpha 4; GFR receptor alpha 4; GFR-alpha-4; GFRA4; GFRA4_HUMAN; Glial cell line derived neurotrophic factor family receptor alpha 4; Neurotrophic factor receptor splice variant A (Gfra4 gene); OTTHUMP00000030106; OTTHUMP00000030107. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul（10nm 15nm 35nm） |
| 研究领域 | 神经生物学 通道蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, Mouse, Rat, ) |
| 产品应用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 27kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GFRA4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存条件 | Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 产品介绍 |
background: The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq] Function: Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla. Subcellular Location: Isoform GFRalpha4a: Cell membrane; Lipid-anchor, GPI-anchor. Isoform GFRalpha4b: Cell membrane; Lipid-anchor, GPI-anchor. Isoform GFRalpha4c: Secreted. Tissue Specificity: Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands. Similarity: Belongs to the GDNFR family. Database links: Entrez Gene: 64096 Human SwissProt: Q9GZZ7 Human Unigene: 302025 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Persephin receptor 是一个新的神经营养因子，属于GDNFR家族，调节GDNF诱导的自动磷酸化和RET受体的活性。他在维持神经系统正常生存中起重要作用。主要表达在正常和恶性甲状腺髓细胞。分子量约为30kDa。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
