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Rabbit Anti-MAT2A/BF555 Conjugated antibody (bs-4054R-BF555)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-4054R-BF555
英文名称 Rabbit Anti-MAT2A/BF555 Conjugated antibody
中文名称 BF555标记的蛋氨酸腺苷转移酶抗体
别    名 MAT2A AdoMet synthetase 2; AdoMet synthetase; AMS 2; AMS2; MAT 2A; MAT II; MATA 2; MATA2; MATII; Methionine adenosyltransferase 2; Methionine adenosyltransferase; Methionine adenosyltransferase II alpha; Methionine adenosyltransferase II; S adenosylmethionine synthetase gamma form; S adenosylmethionine synthetase isoform type 2; SAMS 2; SAMS2; METK1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Zebrafish, Monkey, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Methionine adenosyltransferase (31-80aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
S adenosylmethionine synthetase catalyzes the formation of S adenosylmethionine from methionine and ATP. In mammalian tissues, there are three distinct forms of AdoMet synthases designated as alpha, beta, and gamma. Alpha and beta are expressed only in adult liver, while gamma is widely distributed in extrahepatic tissues.

Function:
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

Subunit:
Homotetramer (MAT-I) or homodimer (MAT-III).

Tissue Specificity:
Expressed in liver.

Post-translational modifications:
S-nitrosylation of Cys-120 inactivates the enzyme (By similarity).

DISEASE:
Defects in MAT1A are the cause of methionine adenosyltransferase deficiency (MATD) [MIM:250850]; also called MAT I/III deficiency. MATD is an inborn error of metabolism resulting in isolated hypermethioninemia. Most patients have no clinical abnormalities, although some neurologic symptoms may be present in rare cases with severe loss of methionine adenosyltransferase activity.

Similarity:
Belongs to the AdoMet synthase family.

Database links:

Entrez Gene: 459363 Chimpanzee

Entrez Gene: 101865874 Cynomolgus Monkey

Entrez Gene: 475770 Dog

Entrez Gene: 4144 Human

Entrez Gene: 232087 Mouse

Entrez Gene: 171347 Rat

Entrez Gene: 695362 Rhesus monkey

Entrez Gene: 323329 Zebrafish

Omim: 601468 Human

SwissProt: Q4R924 Cynomolgus Monkey

SwissProt: P31153 Human

SwissProt: Q3THS6 Mouse

SwissProt: Q5R5H1 Orangutan

SwissProt: P18298 Rat

Unigene: 516157 Human

Unigene: 29815 Mouse

Unigene: 485037 Mouse

Unigene: 144658 Rat

Unigene: 41420 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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