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Rabbit Anti-NPRC/Gold Conjugated antibody (bs-2333R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-2333R-Gold
英文名称 Rabbit Anti-NPRC/Gold Conjugated antibody
中文名称 胶体金标记的利钠肽受体C抗体
别    名 ANP C; ANPC; ANPRC; Atrial natriuretic peptide C type receptor; Atrionatriuretic peptide receptor C; Natriuretic peptide receptor C/guanylate cyclase C; NPR 3; NPR C; NPR3; NPRC; ANPRC_HUMAN.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 心血管  细胞生物  免疫学  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, Cow, Horse, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NPR-C
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Natriuretic peptide receptor C does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.

Function:
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.

Subunit:
Homodimer; disulfide-linked. Dimers can also be formed through the C-terminal cysteine of isoform 2.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the ANF receptor family.

Database links:

Entrez Gene: 281358 Cow

Entrez Gene: 4883 Human

Entrez Gene: 18162 Mouse

Entrez Gene: 25339 Rat

Omim: 108962 Human

SwissProt: P10730 Cow

SwissProt: P17342 Human

SwissProt: P70180 Mouse

SwissProt: P41740 Rat

Unigene: 237028 Human

Unigene: 619466 Human

Unigene: 25259 Mouse

Unigene: 11297 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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