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Rabbit Anti-PRDX5+PRDX6/PE-Cy3 Conjugated antibody (bs-3865R-PE-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-3865R-PE-Cy3
英文名称 Anti-PRDX5+PRDX6/PE-Cy3
中文名称 PE-Cy3标记的过氧化还原酶5/6抗体
别    名 1 Cys; 1 Cys peroxiredoxin; 1 Cys PRX; 1 cysPrx; 24 kDa protein; Acidic calcium independent phospholipase A2; aiPLA2; Antioxidant protein 2; AOP2; Aop2 rs3; Brp 12; Ciliary body glutathione peroxidase; CP 3; GPx; Liver 2D page spot 40; Ltw4; Lvtw 4; Non selenium glutathione peroxidase; NSGPx; ORF06; p29; Peroxiredoxin6; Peroxiredoxin 6; Peroxiredoxin-6; Peroxiredoxin5; Peroxiredoxin 5; Peroxiredoxin-5; PHGPx; Phospholipase A2 lysosomal; PLA2; PRDX 6; Prdx5; PRDX6; PRX; Red blood cells page spot 12; Thiol specific antioxidant protein; AA690119; Prdx6 rs3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  细胞凋亡  干扰素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18/25kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Peroxiredoxin 6 (55-100aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Peroxiredoxin (Prx) is in the peroxidase family, whose mammalian members have been known to contribute to cell proliferation, differentiation and apoptosis. Many isoforms (about 50 proteins), collected in accordance with amino acid sequence homology, particularly the amino terminal region containing active site cysteine residue, and the thiol specific antioxidant activity, distribute throughout all the kingdoms. Mammalian Prx consists of 6 different members grouped into typical 2 Cys, atypical 2 Cys Prx, and 1 Cys Prx. Except PrxVI belonging to the 1 Cys Prx subgroup, the other five 2 Cys Prx isotypes have the thioredoxin dependent peroxidase(TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kDa in molecular size and vary in subcellularlocalization: PrxI, II, and VI in cytosol; PrxIII in mitochondria; PrxIV in ER and secretion; PrxV shows complicated distribution including peroxisome, mitochondria and cytosol.

Subunit:
Monomer.

Subcellular Location:
Mitochondrion. Cytoplasm. Peroxisome.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the peroxiredoxin 2 family.
Contains 1 thioredoxin domain.

Database links:

Entrez Gene: 25824 Human

Entrez Gene: 54683 Mouse

Entrez Gene: 113898 Rat

Omim: 606583 Human

SwissProt: P30044 Human

SwissProt: P99029 Mouse

SwissProt: Q9R063 Rat

Unigene: 502823 Human

Unigene: 279782 Mouse

Unigene: 2944 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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