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Rabbit Anti-ESM1/AP Conjugated antibody (bs-3615R-AP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-3615R-AP
英文名称1 Rabbit Anti-ESM1/AP Conjugated antibody
中文名称 碱性磷酸酶(AP)标记的内皮细胞特异性分子1抗体
别    名 Endocan; Endothelial cell specific molecule 1; ESM 1; ESM-1; ESM 1 secretory protein; ESM1 secretory protein; ESM1_HUMAN; Endothelial cell-specific molecule 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  免疫学  细胞粘附分子  内皮细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, )
产品应用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ESM1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
ESM1 is a secreted dermatan sulfate proteoglycan which is predominantly expressed in the endothelial cells in human lung and kidney tissues. Expression of ESM1 is regulated by cytokines. ESM1 may have a role in lung endothelial cell-leukocyte interactions. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.

Function:
May have potent implications in lung endothelial cell-leukocyte interactions.

Subunit:
Monomer.

Subcellular Location:
Secreted. Peroxisome.

Tissue Specificity:
Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.

Post-translational modifications:
May contain intrachain disulfide bonds.

Similarity:
Contains 1 IGFBP N-terminal domain.

Database links:
UniProtKB/Swiss-Prot: Q9NQ30.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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