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Rabbit Anti-Phospho-PLC beta3 (Ser1105)/APC Conjugated antibody (bs-3341R-APC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-3341R-APC
英文名称 Anti-Phospho-PLC beta3 (Ser1105)/APC
中文名称 APC标记的磷酸化磷酯酶Cβ3抗体
别    名 Phospholipase C beta 3; Phospholipase C beta 3 (phosphatidylinositol specific); PLC beta 3; PLCB3 antibody 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3; Phosphoinositide phospholipase C; PLCB3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 肿瘤  免疫学  信号转导  转录调节因子  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, )
产品应用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 136kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human PLC beta3 around the phosphorylation site of Ser1105
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Phospholipase C is a key enzyme in phosphatidylinositol (PIP2) metabolism and lipid signaling pathways. The Phospholipase C family consists of 13 isozymes split between six subfamilies. Phospholipase C beta is activated by G protein subunits.

Function:
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

Subunit:
Interacts with SHANK2. Interacts with LPAR2.

Subcellular Location:
Membrane; Peripheral membrane protein.

Similarity:
Contains 1 C2 domain.
Contains 1 PI-PLC X-box domain.
Contains 1 PI-PLC Y-box domain.

Database links:

Entrez Gene: 5331 Human

Entrez Gene: 18797 Mouse

Entrez Gene: 29322 Rat

Omim: 600230 Human

SwissProt:  Human

SwissProt: P51432 Mouse

SwissProt: Q99JE6 Rat

Unigene: 523761 Human

Unigene: 591953 Human

Unigene: 273204 Mouse

Unigene: 16983 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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