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Rabbit Anti-Phospho-FRA1 (Ser265)/BF555 Conjugated antibody (bs-3158R-BF555)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-3158R-BF555
英文名称 Rabbit Anti-Phospho-FRA1 (Ser265)/BF555 Conjugated antibody
中文名称 BF555标记的磷酸化FRA-1蛋白抗体
别    名 FOSL1; Fos related antigen 1; FOS L1; FOS like antigen 1; FOSL 1; FOSL1 protein; FRA 1; Fos-related antigen 1; FOSL1_HUMAN; FRA-1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human FRA1 around the phosphorylation site of Ser265
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq].

Subunit:
Heterodimer.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the bZIP family. Fos subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.

Database links:

Entrez Gene: 8061 Human

Omim: 136515 Human

SwissProt: P15407 Human

Unigene: 283565 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

FOSL1蛋白对细胞因子、生长因子、感染或致癌刺激等生理或病理信号发生应答,调节基因的转录, 参与细胞的增殖、分化等过程。 FOSL1在肿瘤形成及发展过程中, 通过促进细胞增殖、抑制分化、促进肿瘤细胞的侵袭和转移等过程发挥作用。
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