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Rabbit Anti-CD69/BF594 Conjugated antibody (bs-2499R-BF594)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-2499R-BF594
英文名称1 Rabbit Anti-CD69/BF594 Conjugated antibody
中文名称 BF594标记的活化诱导分子CD69抗体
别    名 CLEC2C; AIM; Early activation antigen CD69; Early T-cell activation antigen p60; GP32/28; Leukocyte surface antigen Leu-23; MLR-3; EA1; BL-AC/P26;C-type lectin domain family 2 member C.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  干细胞  糖尿病  细胞表面分子  自然杀伤细胞  淋巴细胞  t-淋巴细胞  b-淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Dog, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD69
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011]

Function:
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.

Post-translational modifications:
Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.

Similarity:
Contains 1 C-type lectin domain.

Database links:

Entrez Gene: 969 Human

Entrez Gene: 12515 Mouse

Entrez Gene: 29187 Rat

Omim: 107273 Human

SwissProt: Q07108 Human

SwissProt: P37217 Mouse

Unigene: 208854 Human

Unigene: 74745 Mouse

Unigene: 23779 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD69属于C-型凝集素受体家族,也是NK细胞信号传导基因复合体家族的一员,是一种Ⅱ型跨膜糖蛋白.
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