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Rabbit Anti-Nuclear Pore Complex Proteins/Nup107/FITC Conjugated antibody (bs-11678R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11678R-FITC
英文名称 Rabbit Anti-Nuclear Pore Complex Proteins/Nup107/FITC Conjugated antibody
中文名称 FITC标记的核孔复合体蛋白抗体
别    名 107 kDa nucleoporin; NPC proteins; NU107_HUMAN; Nuclear pore complex protein Nup107; Nucleoporin 107kDa; Nucleoporin Nup107; NUP 107; NUP 84; NUP107; NUP153; NUP155; NUP84; NUP98.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 染色质和核信号  神经生物学  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Pig, Horse, Rabbit, )
产品应用 Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 106kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nuclear Pore Complex Proteins (501-600aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

Function:
Essential component of nuclear pore complex. Required for the assembly of peripheral proteins into the nuclear pore complex.

Subunit:
Forms part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus.

Subcellular Location:
Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the nuclear pore. During mitosis, localizes to the kinetochores.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the nucleoporin Nup84/Nup107 family.

Database links:

Entrez Gene: 57122 Human

Entrez Gene: 103468 Mouse

Entrez Gene: 116555 Rat

Omim: 607617 Human

SwissProt: P57740 Human

SwissProt: Q3TT06 Mouse

SwissProt: Q3V395 Mouse

SwissProt: Q569X8 Mouse

SwissProt: Q8BH74 Mouse

SwissProt: P52590 Rat

Unigene: 524574 Human

Unigene: 12568 Mouse

Unigene: 11398 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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