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Rabbit Anti-Gbx1/AP Conjugated antibody (bs-11660R-AP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11660R-AP
英文名称1 Rabbit Anti-Gbx1/AP Conjugated antibody
中文名称 碱性磷酸酶(AP)标记的肠和大脑特定同源蛋白1抗体
别    名 Gastrulation and brain specific homeobox protein 1; Gastrulation and brain-specific homeobox protein 1; Gastrulation brain homeo box 1; Gastrulation brain homeobox 1; Gbx1; GBX1_HUMAN; Homeobox protein GBX-1; Homeobox protein GBX1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  染色质和核信号  神经生物学  信号转导  Alzheimer's  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Rabbit, Zebrafish, Sheep, Fruit Fly, Chimpanzee, mpanzee,)
产品应用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Gbx1 (201-300aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The homeobox is DNA sequence that is approximately 180 base pairs long that is involved in all steps of the developmental regulation of animals, fungi and plants, from embryogenesis to cell differentiation. The homeobox encodes a protein domain of about 60 amino acids, called the homeodomain, that can bind to DNA. The gastrulation brain homeobox 1 (GBX1) gene, along with another homeobox gene (EN2), maps to chromosome 7q36, and is expressed in septal and pallidal areas and in the basal forebrain cholinergic system, an area implicated in Alzheimer’s disease. The GBX1 gene encodes the GBX1 protein, which localizes to the nucleus and contains 1 homeobox DNA-binding domain.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 2636 Human

Entrez Gene: 231044 Mouse

Entrez Gene: 246149 Rat

Omim: 603354 Human

SwissProt: Q14549 Human

SwissProt: P82976 Mouse

Unigene: 647114 Human

Unigene: 246596 Mouse

Unigene: 92432 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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