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Rabbit Anti-Cpt1c/BF350 Conjugated antibody (bs-11416R-BF350)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11416R-BF350
英文名称1 Rabbit Anti-Cpt1c/BF350 Conjugated antibody
中文名称 BF350标记的脑型肉碱棕榈酰转移酶1C抗体
别    名 CPT1-C; Carnitine acyltransferase like protein 1; Carnitine acyltransferase like protein1; Carnitine O palmitoyltransferase I, brain isoform; Carnitine palmitoyltransferase 1, brain; Carnitine palmitoyltransferase 1C; Carnitine palmitoyltransferase I related C; Carnitine palmitoyltransferase1C; CAT L1; CATL 1; CATL1; CPT 1 like pseudogene; Cpt 1c; CPT 1P; CPT I C; Cpt1 c; CPT1 like pseudogene; CPT1P ; CPTIC.CPT1C_HUMAN  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  细胞生物  神经生物学  信号转导  内分泌病  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 88kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cpt1c (121-170aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.

Subcellular Location:
Mitochondrion outer membrane; Multi-pass membrane protein

Tissue Specificity:
Expressed predominantly in brain and testis.

Similarity:
Belongs to the carnitine/choline acetyltransferase family.

Database links:
UniProtKB/Swiss-Prot: Q8TCG5.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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