| 产品编号 | bs-11274R-PE-Cy5.5 |
| 英文名称 | Rabbit Anti-Complement C4 / C4a/PE-Cy5.5 Conjugated antibody |
| 中文名称 | PE-Cy5.5标记的过敏毒素C4/补体C4抗体 |
| 别 名 | C4a anaphylatoxin; Complement C4-A alpha chain; complement C4-A proprotein; Acidic C4; Acidic complement C4; Basic C4; Basic complement C4; C4 Anaphylatoxin; C4 complement C4d region; complement C4 alpha chain; C4A; C4A13; C4A2; C4A3; C4A4; C4A6; C4A91; C4B; C4B1; C4B12; C4B2; C4B3; C4B5; C4F; C4S; CH; Chido form of C4; CO4; Complement C4 A; Complement C4 B; Complement C4B; Complement component 4A (Rodgers blood group); Complement component 4A; Complement component 4B (Childo blood group); Complement component 4B; Complement component C4B; CPAMD2; CPAMD3. RG; Rodgers Form Of C4. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, ) |
| 产品应用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 8/84/190kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Complement C4 C4a anaphylatoxin or complement C4 alpha chain |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. Function: C4 plays a central role in the activation of the classical pathway of the complement system. It is processed by activated C1 which removes from the alpha chain the C4a anaphylatoxin. Subunit: This protein is synthesized as a single-chain precursor and, prior to secretion, is enzymatically cleaved to form a trimer of non-identical chains (alpha, beta and gamma). Subcellular Location: Secreted. DISEASE: Defects in C4A are the cause of complement component 4A deficiency (C4AD). A rare defect of the complement classical pathway associated with the development of autoimmune disorders, mainly systemic lupus with or without associated glomerulonephritis. Similarity: Contains 1 anaphylatoxin-like domain. Contains 1 NTR domain. Database links: Entrez Gene: 100293534 Human Entrez Gene: 100507685 Human Entrez Gene: 720 Human Entrez Gene: 721 Human Omim: 120810 Human SwissProt: P0C0L4 Human SwissProt: P0C0L5 Human Unigene: 534847 Human Unigene: 720022 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
